Natural history keynote talk 
John Yates

Progress in the application of less invasive therapeutic techniques to the management of renal lesions associated with TSC                     
John Hulbert                                                                                 

TSC and renal AMLs: long term outcome in a case series from a renal referral centre                      
Rosa Montero

The management of over 70 patients with tuberous sclerosis and renal angiomyolipomata 
Prasanna Sooriakumaran

Epidemiology keynote talk                                              
Finbar O’Callaghan

Tuberous sclerosis 2000 study: early intellectual development
Patrick Bolton

Prevalence of subependymal giant cell tumours in patients with tuberous sclerosis and a review of the literature                             
Miraude Adriaensen

The TSC database: a valuable resource for the TSC community
Rosemary Ekong

TSC Natural History Database 
Vicky Whittemore

Keynote talk
John Bissler

Update on the US multi-centre rapamycin angiomyolipoma trial and recent TSC preclinical studies
Sandra Dabora

Safety and efficacy of RAD001 (Everolimus) for the treatment of subependymal giant cell astrocytoma in pediatric and adult patients with TSC
Darcy Krueger

TESSTAL: a trial of the safety and efficacy of sirolimus (rapamycin) therapy for renal angiomyolipomas in patients with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis                       
Mark Davies

Functional analysis of TSC1 and TSC2 variants  
Mark Nellist

Development of a xenograft model using TSC2-null skin tumour cells from patients with tuberous sclerosis                                                       
Shaowei Li

Keynote talk           
Petrus de Vries

The role of the TSC genes in learning, social behaviour and synaptic plasticity   
Susanna Goorden

Pre-post seizure onset, cognitive development in infants with TS
Ayla Humphrey

Abnormalities in the white matter tracts and corpus callosum in adults with TSC and normal IQ evidence from diffusion tensor imaging
Deborah McCartney

Communication between doctors, schools, and parents of children with TSC
Dena Hook

Genetics keynote talk 
Lisa Henske

Defects in cell polarity underlie renal cystic disease in tuberous sclerosis
Cleo Bonnet

Using an in vitro mTOR kinase assay to further characterise the mTOR pathway
Elaine Dunlop

mTOR is a component of the molecular clock which controls vasculogenesis in the developing lung: implications for understanding angiogenesis in TSC & LAM 
Stephen Land                                                                  

Neuroanatomy keynote speaker                                           
Bernd Scheithauer

Epilepsy keynote speaker                                               
Finbar O’Callaghan

Effect of RAD001 (Everolimus) on epilepsy and neurorecognition in patients with TSC   
Darcy Krueger

Natural course of epilepsy and mental retardation in children with pre- or perinatal diagnosis of  TSC
Sergiusz Joswiak

Late breaking research/poster session

Conclusion of Scientific Research Conference

1300 - 1400   Lunch